Technical advances in recent years have made the application of controlled low temperatures a feasible proposition in many branches of surgery. The benefits of cold have been appreciated for many thousands of years. In the last decade there has been a proliferation of reports on the uses of cryotherapy; nevertheless, many of the applications are still experimental, or await the test of time. Cryotherapy is the deliberate destruction of tissue by application of extreme cold. This review highlights on the various aspect like the different terms, techniques, principles and applications of cryotherapy. Cryotherapy now days getting popularity due to cure rate as well as the advancement in the equipments.
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